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The Common Era history of effective moisture in the Central Andes is poorly understood, as most Andean proxy records reflect large-scale atmospheric circulation over the South American lowlands rather than localized precipitation vs. evaporation. Here we present 1800-year leaf wax hydrogen and carbon isotope sedimentary records from Lake Chacacocha (13.96°S, 71.08°W, 4,860 m asl.) in the Central Andes. Leaf wax δ2H from different chain lengths offers information about large-scale atmospheric conditions and local-scale effective moisture. Our leaf wax δ2H data record a gradual intensification of the South American summer monsoon (SASM) beginning around ~1250 CE, prior to the external forcings of the Little Ice Age (LIA). Despite peak SASM intensification, our leaf wax δ13C data reveal a locally arid interval between ca. 1600 and 1800 CE. The arid interval was most likely driven by enhanced evaporation and reduced local precipitation, as indicated by the hydrogen isotope fractionation between mid- and long-chain n-alkanes as well as by climate model simulations. Our results help to reconcile conflicting interpretations of the SASM, glacial, and lake-level histories in the Central Andes during the Common Era. 

ABSTRACT In the 12 years since Dudgeonet al. (2006) reviewed major pressures on freshwater ecosystems, the biodiversity crisis in the world's lakes, reservoirs, rivers, streams and wetlands has deepened. While lakes, reservoirs and rivers cover only 2.3% of the Earth's surface, these ecosystems host at least 9.5% of the Earth's described animal species. Furthermore, using the World Wide Fund for Nature's Living Planet Index, freshwater population declines (83% between 1970 and 2014) continue to outpace contemporaneous declines in marine or terrestrial systems. The Anthropocene has brought multiple new and varied threats that disproportionately impact freshwater systems. We document 12 emerging threats to freshwater biodiversity that are either entirely new since 2006 or have since intensified: (i) changing climates; (ii) e‐commerce and invasions; (iii) infectious diseases; (iv) harmful algal blooms; (v) expanding hydropower; (vi) emerging contaminants; (vii) engineered nanomaterials; (viii) microplastic pollution; (ix) light and noise; (x) freshwater salinisation; (xi) declining calcium; and (xii) cumulative stressors. Effects are evidenced for amphibians, fishes, invertebrates, microbes, plants, turtles and waterbirds, with potential for ecosystem‐level changes through bottom‐up and top‐down processes. In our highly uncertain future, the net effects of these threats raise serious concerns for freshwater ecosystems. However, we also highlight opportunities for conservation gains as a result of novel management tools (e.g. environmental flows, environmental DNA) and specific conservation‐oriented actions (e.g. dam removal, habitat protection policies, managed relocation of species) that have been met with varying levels of success. Moving forward, we advocate hybrid approaches that manage fresh waters as crucial ecosystems for human life support as well as essential hotspots of biodiversity and ecological function. Efforts to reverse global trends in freshwater degradation now depend on bridging an immense gap between the aspirations of conservation biologists and the accelerating rate of species endangerment.